Yes. Synthetic indices and crypto trade 24 hours a day, every day, including weekends and holidays. The only pause is weekly maintenance on Sunday from 21:00 to 22:00 UTC (Monday 6:00 to 7:00 Japan time).
Currency pairs, gold and silver follow the markets behind them, which close at weekends:
- Currency pairs close on Friday at 21:00 UTC and reopen on Sunday at 22:00 UTC.
- Gold and silver close on Friday at 20:00 UTC and reopen on Sunday at 23:00 UTC.
In Japan time, that's from Saturday morning until Monday morning.
You can use HIGH/LOW, TOUCH and SPREAD at weekends on any asset that's open. See Trading hours for the full schedule.
Related: Trading hours · What are synthetic indices? · When and how can I trade synthetic indices? · When is scheduled maintenance?